Mozobil 24mg contains the active substance Plerixafor which blocks a protein on the surface of stem cells in the blood. This protein “ties” blood stem cells to the bone marrow. Plerixafor improves the release of stem cells into the bloodstream (mobilization). The stem cells can then be removed with an apheresis machine, and subsequently frozen and stored until your transplant.
f the mobilization is insufficient, plerixafor is intended to help in the recovery of stem cells from the blood for transplantation in patients with lymphoma (a cancer that affects the white blood cells) and multiple myeloma (a cancer that plasma cells in the bone marrow attacks) suffer ,
WHAT YOU NEED TO CONSIDER BEFORE USING IT?
Mozobil MUST NOT be applied,
- if you are allergic (hypersensitive) to plerixafor or any of the other ingredients of plerixafor (listed in section 6, “What Mozobil contains’).
Take special care when taking plerixafor is required
Tell your doctor:
- if you suffer from heart problems or have suffered.
- if you suffer from kidney problems. Your doctor adjusts the dose.
- when there are high white blood cell numbers with you.
- when there are low Bluttplättchenzahlen yours.
- if you are filled close in the past, when rising or setting of impotence
have you felt dizzy or have fallen in injections fainted.
if you are under 18 years. The effects of Mozobil on children and adolescents have not been studied.
Your doctor performs regular blood tests by to monitor your blood cell count.
It is not recommended to use plerixafor for stem cell mobilization if you suffer from leukemia (a cancer that affects the blood or bone marrow).
In Mozobil with other medicinal products
Please inform your doctor or pharmacist if you are taking other medicines / or have recently taken / used, even if it is not prescribed.
pregnancy and breast feeding period
You should not use Mozobil if you are pregnant, there is no experience with Mozobil in pregnant women are present. It is important that you tell your doctor if you are pregnant or might be or are planning a pregnancy. Contraception is recommended if you are of childbearing age.
You should not breastfeed if you are taking Mozobil, since it is not known if Mozobil is excreted in human milk.
Driving and using machines
Mozobil may cause dizziness and fatigue. That’s why you should not get behind the wheel of a vehicle, if you feel dizzy, tired or unwell.
Important information about some of the ingredients of Mozobil
Mozobil is essentially sodium-free. It contains less than 1 mmol sodium (23 mg) per dose.